Detalhe da pesquisa
1.
Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial.
PLoS Med
; 16(4): e1002790, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31039172
2.
Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis-Specific T-Cell Responses.
J Infect Dis
; 217(11): 1782-1792, 2018 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29546381
3.
Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity.
J Infect Dis
; 213(5): 824-30, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26450421
4.
Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model.
J Infect Dis
; 211(9): 1499-509, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381367
5.
Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate tuberculosis vaccine, MVA85A, alone and in combination.
J Infect Dis
; 209(8): 1259-68, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24273174
6.
Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
BMC Infect Dis
; 14: 314, 2014 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24912498
7.
Inhaled aerosol viral-vectored vaccines against tuberculosis.
Curr Opin Virol
; 66: 101408, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574628
8.
Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial.
Lancet Infect Dis
; 24(3): 285-296, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012890
9.
Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
Lancet Infect Dis
; 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621405
10.
Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study.
Lancet Microbe
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703782
11.
A human challenge model for Mycobacterium tuberculosis using Mycobacterium bovis bacille Calmette-Guerin.
J Infect Dis
; 205(7): 1035-42, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396610
12.
Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants.
Nat Commun
; 13(1): 6594, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329009
13.
Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Sci Rep
; 12(1): 7808, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35552463
14.
The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells.
F1000Res
; 10: 257, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33976866
15.
Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination.
Front Immunol
; 12: 798207, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35069580
16.
A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates.
NPJ Vaccines
; 6(1): 3, 2021 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397986
17.
Phase I Trial Evaluating the Safety and Immunogenicity of Candidate TB Vaccine MVA85A, Delivered by Aerosol to Healthy M.tb-Infected Adults.
Vaccines (Basel)
; 9(4)2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923628
18.
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults.
Vaccine
; 38(4): 779-789, 2020 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31735500
19.
Current approaches toward identifying a correlate of immune protection from tuberculosis.
Expert Rev Vaccines
; 18(1): 43-59, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30466332
20.
Tools for Assessing the Protective Efficacy of TB Vaccines in Humans: in vitro Mycobacterial Growth Inhibition Predicts Outcome of in vivo Mycobacterial Infection.
Front Immunol
; 10: 2983, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31998295